pentobarbital will lower the extent or impact of fosphenytoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.

pentobarbital improves toxicity of methoxyflurane by expanding metabolism. Contraindicated. Increased metabolism of methoxyflurane to nephrotoxic compounds.

Watch Closely (one)pentobarbital will lessen the extent or impact of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will lower the extent or impact of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital will reduce the level or impact of sunitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

Drugs that have stage therapy affiliated with Every prescription. This restriction generally necessitates that certain criteria be satisfied just before approval to the prescription.

With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs.

fentanyl transmucosal and pentobarbital both maximize sedation. Avoid or Use Alternate Drug. Limit use to sufferers for whom option cure solutions are inadequate

pentobarbital will lessen the extent or impact of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will decrease the level or influence of tacrolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

pentobarbital will lessen the extent or outcome of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.

pentobarbital will minimize the extent or outcome of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of fentanyl with CYP3A4 inducers could lead into a reduce in fentanyl plasma concentrations, insufficient efficacy or, quite possibly, progress of a withdrawal syndrome in the affected individual that has created Actual physical dependence to fentanyl.

Warning when discontinuing CYP3A4 inducers that are coadministered with website hydrocodone; plasma concentrations of hydrocodone may perhaps enhance and can lead to most likely fatal respiratory depression

pentobarbital will lessen the level or result of buprenorphine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.